miRbiom, CSIR-IHBT

The miRbiom server is a miRNA profiler software. The purpose of the miRbiom server is to predicted an accurate profie the miRNAs without any need for miRNA-sequencing or array profiling experiments. For any given condition, the users needs to provide the transcriptome profiling data and just run the software after loading it. The data passed through causal networks for miRNAs which explain the miRNA biogenesis. In term, the network is mapped for the component genes expression data on which XGBoost regression machine learning system takes decision. Finally the XGBoost machine learning system gives the relative expression scores of all the miRNAs for the given condition. It generates interactive plot of expression profiles of different miRNAs. Selections can be made to study the miRNA targets for their functional enrichment and associated pathways. miRNA target information comes from various databases like miRTarbase etc. Provisions were also made for mapping the miRNA targets collectively and displaying them in maps of KEGG pathways.

 

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