Biomarker of Cancer Stem Cell Database abbreviated as BCSCdb is a repository of information about Cancer Stem Cells (CSCs) biomarkers. This CSC database compiles high throughput and low throughput biomarkers obtained from CSCs of ten different types of cancers as shown on the browse page. It comprises of three entity tables. 1) Biomarker table, 2) Therapeutic table, and 3) Interaction table.
The following terms are used in the database:
1)The Confidence score is based on the method of biomarker detection. The higher the value the higher the reliability of the biomarker.
2)The Global Score is the frequency of the biomarker reported in the database. A higher score indicates a biomarker can be observed across all types of cancer, a lower score suggests a biomarker is specific to a particular type of cancer.
3)The genes or proteins identified in primary tissue using low-throughput methods e.g. Western blotting, and RT-PCR are referred to here as CSCs clinical biomarkers.
4)The CSCs biomarkers, targeted by drugs that are in a clinical trial for targeting the CSCs population are referred to here as a clinical trial biomarker.