ICGEB, NEW DELHI
Translational Bioinformatics Group, International Center for Genetic Engineering & Biotechnology (ICGEB)
The bioinformatics center at ICGEB is focused on high-throughput data analysis in healthcare, agriculture, and biotechnology. The center has extensively employed artificial intelligence to solve classification problems in diverse domains. The center collaborates with DBT-supported bioinformatics groups at AIIMS-Delhi, IIIT-Delhi, Delhi University, and Aligarh Muslim University to work on NNPs.
Development and application of computational biology tools to address research problems in Parasite Biology, Medical research, Synthetic Biology and Plant Biology. Development of Artificial Intelligence-based tools for healthcare.
This center's studies on human infections caused by parasites like Plasmodium falciparum and viruses such as SARS-CoV-2 have garnered attention and featured in the news (IANS & ScienceDaily). Deep learning-based image-data predictions in glaucoma empower clinicians to decide on treatment options. A patent has been filed for this technology.
The Center at ICGEB have successfully conducted projects aimed at translational outcomes benefiting patient care, assisting medical practitioners, and contributing to drug discovery programs. Some of the studies’ outcomes include AI-based classification tools for cancer staging, surgery outcome prediction (Glaucoma), development of pharmacophore models (COVID-19), prognostic biomarkers (triple-negative breast cancer) identification, etc.
This center has a powerful computational infrastructure, an IBM POWER 9 HPC system, and the essential hardware for cutting-edge bioinformatics research. The center has developed several web servers and databases publicly available at http://bioinfo.icgeb.res.in. Notably, the VirulentPred web server developed by the center is widely used and highly cited by the worldwide science community.
The center has expertise in applying artificial intelligence to solve classification problems in biotechnology, health sciences, and agriculture.
NNP partners are affiliated with tertiary care referral centers, such as AIIMS in New Delhi, which are crucial in recruiting patients for research in common diseases and rare disorders. This enables us to generate appropriate research datasets amenable to modern data mining and classification techniques for reliable and impactful outcomes.
