{"id":2028,"date":"2024-01-10T05:52:46","date_gmt":"2024-01-10T05:52:46","guid":{"rendered":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/?page_id=2028"},"modified":"2024-02-07T10:31:03","modified_gmt":"2024-02-07T10:31:03","slug":"overview_bose_institute","status":"publish","type":"page","link":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/overview_bose_institute\/","title":{"rendered":"overview_bose_institute"},"content":{"rendered":"\n

\n\t\tBose Institute, Kolkata\n\t<\/h4>\n

\n\t\tA multi-channel community campaign to connecting users\n\t<\/h2>\n\t

Bioinformatics Centre at Bose Institute, funded by Department of Biotechnology, is more than 3 decades old. After the completion of earlier center’s project, a new project has started as a new center since 2022 with the objectives mentioned below.<\/p>\n\t

Primary Objective<\/strong><\/p>\n

1. Understanding the cellular pathways and strategies adopted by the cells at molecular level that causes a malfunction leading to specifically Breast, Ovarian, Cervical and Lung cancer<\/p>\n

2. Understanding the structural biology of the macromolecules involved in the diseases mentioned above, including their structural dynamics, interactions that determine their function, leading to the design of therapeutic peptides\/small molecules to combat the diseases<\/p>\n

Secondary Objective<\/strong><\/p>\n

1. Unravelling the contribution of Human and Microbiome in health and disease<\/p>\n

2. Design of therapeutic molecules against plant pathogens, specifically against diseases of Leaf, e.g. Leaf Blight disease.<\/p>\n

3. Revealing the molecular nature of stress resilience in a cultivated crop Training, workshop, teaching Development of Tools\/software and databases<\/p>\n\t

The centre has Developed databases and tools Achieved substantial understating on the molecular mechanism of allostery. Published research papers.<\/p>\n

Cancer Stem Cells\u00a0 biomarker database (BCSCdb)\u00a0http:\/\/dibresces.jcbose.ac.in\/ssaha4\/bcscdb\u00a0<\/a> Developed ML based tools:<\/p>\n

(a) LncRTPred predicts LncRNA targets https:\/\/doi.org\/10.1002\/iub.2778<\/a><\/p>\n

(b) TbAMLPred is a non-invasive mode of AML detection https:\/\/doi.org\/10.1016\/j.compbiolchem.2023.107859<\/a><\/p>\n

 <\/p>\n

It integrates expertise in Plant science, Microbiology, Structural Biology with full time Bioinformaticians working in the areas of molecular Structure and dynamics, Genomics, proteomics, Transcriptomics.<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n\n","protected":false},"excerpt":{"rendered":"

Bose Institute, Kolkata A multi-channel community campaign to connecting users Bioinformatics Centre at Bose Institute, funded by Department of Biotechnology, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}}},"_links":{"self":[{"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/pages\/2028"}],"collection":[{"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/comments?post=2028"}],"version-history":[{"count":2,"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/pages\/2028\/revisions"}],"predecessor-version":[{"id":3011,"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/pages\/2028\/revisions\/3011"}],"wp:attachment":[{"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/media?parent=2028"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}