{"id":2259,"date":"2024-01-11T07:34:46","date_gmt":"2024-01-11T07:34:46","guid":{"rendered":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/?page_id=2259"},"modified":"2024-02-08T07:16:01","modified_gmt":"2024-02-08T07:16:01","slug":"overview_nii","status":"publish","type":"page","link":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/overview_nii\/","title":{"rendered":"overview_nii\ufffc"},"content":{"rendered":"\n

\n\t\tNII, New Delhi\n\t<\/h4>\n

\n\t\tBioinformatics and Computational Biology Centre,\n\t<\/h2>\n\t

Over the years, the centre engaged in diversified research areas, spanning systems biology, chemical biology, structural biology, machine learning, and other disciplines. Equipped with state-of-the-art computing resources, the bioinformatics centre supports advanced research projects and has granted over 15 PhD degrees to accomplished scholars.<\/p>\n

1. Advanced research in structural bioinformatics for development of multi-scale modelling tools for: In silico identification of microbiome associated metabolites and biochemical pathways affecting cellular processes in host.Genome scale prediction of signaling (Protein-Protein) &amp; regulatory (Protein-RNA\/DNA)networks & Analysis of disease associated mutations in coding and non-coding regions<\/p>\n

2. Collaborative research programs with experimental research groups in India working on major disease biology projects like malaria, tuberculosis and cancer for facilitating data driven research.<\/p>\n

3. Initiating consortium projects involving structural bioinformatics research groups in India in collaboration with leading international bioinformatics centers to build major resources.<\/p>\n

4. High end infrastructure building for providing hardware\/software resources for MD simulations, drug design and NGS data analysis.5. Manpower development in bioinformatics and computational biology by long\/short term training and advanced work.”<\/p>\n\t\t\t\t\"c7LvBoFlzuVk-Akshay_flowgram\"\n\t

The centre excels in Bioinformatics\/Computational Biology, developing 15+ databases\/servers and publishing 75+ impactful papers in esteemed journals. It pioneers computational methods for protein substrate prediction and identifies key biosynthetic pathways. Our recent ML approach to predict modulators of protein-protein interactions, phosphorylation sites and small-ORFs has been published in reputed journals<\/p>\n

The centre has a robust computational infrastructure, encompassing high-performance computing (HPC) systems with A100 and V100 GPUs, enabling cutting-edge bioinformatics research. We have also developed numerous tools, web servers, and databases listed at http:\/\/202.54.249.134\/BIC-NII\/databases-servers\/<\/a>, empowering advanced analysis, structural predictions, and genomic exploration in the field.<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n\t

The centre uses cutting-edge state-of-the-art AI\/ML\/DL and LLM in the areas of genomics, structural biology and immunology.<\/p>\n

The NNP is focused on the discovery of novel drug targets for drug-resistant Mycobacterium tuberculosis using a multi-disciplinary approach in collaboration with leading experimental research groups working on tuberculosis and other researchers with expertise in structural biology and pathway modelling<\/p>\n\n","protected":false},"excerpt":{"rendered":"

NII, New Delhi Bioinformatics and Computational Biology Centre, Over the years, the centre engaged in diversified research areas, spanning systems […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}}},"_links":{"self":[{"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/pages\/2259"}],"collection":[{"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/comments?post=2259"}],"version-history":[{"count":4,"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/pages\/2259\/revisions"}],"predecessor-version":[{"id":3052,"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/pages\/2259\/revisions\/3052"}],"wp:attachment":[{"href":"https:\/\/apexbtic.icgeb.res.in\/btisnet\/wp-json\/wp\/v2\/media?parent=2259"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}